Operation and Cleaning of Liquid Filter Press

1.0         Purpose

1.1        To define a standard operating and cleaning procedure of Liquid Filter Press.

2.0          Scope

2.1          This procedure is applicable for Liquid Filter Press in liquid production area of “NAME” Pharmaceuticals Ltd.

 

3.0       Responsibility

3.1.       Only trained operator is responsible for normal operation. He/ She inform the supervisor  about any deviation from normal operation. He also maintains logbook.

3.2.       Sr. Officer- Production/Officer- Production is responsible for monitoring day to day activity.

 

 

4.0      Abbreviations and Definitions

4.1        None

  

5.0     Materials and Equipment

5.1        Nylon Scrubber

5.2        Lint free cloth

5.3        Detergent Solution, 0.4% (w/v) Sodium lauryl Sulphate:  4 gm Sodium lauryl Sulphate is   dissolved in 1.0 liter of portable / tap water to prepare detergent solution.

 

6.0     Precaution / Health and Safety Considerations

6.1          Don’t press electric switch with wet hand.

6.2          Ensure the surrounding areas are cleaned before starting operation.

6.3          Before set the filter cloth; soak it in purified water.

 

7.0       Procedure

7.1       Operation Procedure

7.1.1     Check that all parts are clean and dry.

7.1.2     Affix the “Operation Status” label.

7.1.3     Fit S.S. Plate, frame, filter cloth in correct way and correct position, arrange them in filter chamber, fit the screw and tighten the lid screw as follows:

Ø  Filter press consists of 10 sets of filter plates, sieves and filter cloth.

Ø  Place one set of filter disc (SS plate, sieve, filter cloth, filter plate) repeat the same for all 10 sets.

Ø  They are fitted with 4 long bolts and this assembly is fitted in to the chamber along with long bolt in the center.

Ø  Placed the center rod in proper position and tighten. Tighten the side supporting rods and center rod simultaneously.

Ø  Place the rubber gasket properly, so that there is no leakage when tightened up in the assembly.

Ø  Close the lid and tighten it properly with side clamps.

 7.1.4     Connect the filter press with storage tank outlet valve with required length of clean, dry flexible hose pipe.

7.1.5     Open the valve of storage tank and filter press.

7.1.6     Switch on power supply and start filter press pump.

7.1.7     Keep air vent valve open initially, when solution start to come out close air vent valve. Solution starts to come out from the assembly. Take approximately 100 ml in glass beaker to check clarity of solution. If not satisfactory reset filter assembly and again start filtration.

7.1.9     Maintain records of Liquid Filter Press Logbook.

 

7.2       Cleaning Procedure:

7.2.1         Ensure all the material is removed from the equipment.

7.2.2         Remove the product status label and affix “To Be Cleaned” label.

7.2.3         Spray potable water on the outer surface of the filter press to remove the adhered material.

7.2.4         Open lid of filter assembly, unscrew the filter assembly and pullout whole assembly. Dismantle             the plate and frame unit, filter cloth/ pad.

7.2.5         Clean the filter cloth with detergent solution (0.4% w/v sodium lauryl sulphate) and finally wash             with purified water. Then dry the filter cloth by dryer keep in clean poly bag.

7.2.6         Clean the Dismantle part with potable water then detergent solution (0.4% w/v sodium lauryl sulphate) and finally wash with purified water.

7.2.7         Assemble the filter press without filter cloth.

7.2.8         Take 150 Liter hot purified water (75⁰c) in SS container.

7.2.9         Connect the filter press to SS container, start recirculation for 10 minutes, drain it.

7.2.10        Dismantle the filter press again and wipe the inner and outer surface with dry lint free cloth.

7.2.11        Reassembly the filter press with clean cloth.

7.2.12     Before machine operation, it is mandatory to run machine with hot purified water (75⁰ C) at least 10 minutes.

 

7.3    Machine operator / worker will request Production Officer and QA Officer for checking visual inspection.           

7.4        At first Production Officer will check the filter press and its surroundings, and then QA Officer will check the filter press and its surroundings. If it found satisfactory result, then he / she will issue “Cleaned” label.

7. 5       Record in Liquid filter press logbook and attach the label of “Cleaned” in the machine.

7.7     After cleaning the filter press if it remains without operation for next 72 hour, will undergo re-cleaning operation.

 

 

8.0      Reference Document

8.1        In House

  

9.0       Annexure       

9.1        Annexure- I       : Format of Machine Logbook

 

10.0    Revision History 

Revision No.	Brief reason for the revision	Effective Date	Remarks
01	New

  

11.0     Training 

11.1      Head of Production or his nominee give the training of production operator and worker.